Publikationsverzeichnis

List of publications ·

1) J. Augustin, G. Dannhardt, W. Kiefer, S. Laufer: (6,7-Diaryldihydropyrrolizin-5-yl)acetic Acids, a Novel Class of Potent Dual Inhibitors of Both Cyclooxy-genase and 5-Lipoxygenase, J. Med. Chem., 37, 1894-1897 (1994)

2) G. Dannhardt und W. Kiefer: C-5 Functionalized 6,7-Diphenyl-2,3-dihydro-1H-pyrrolizines as Inhibitors of Bovine Cyclooxygenase and 5-Lipoxygenase, Arch. Pharm (Wein heim) 327, 509-514 (1994).

3) G.Dannhardt, W.Kiefer, G.Lambrecht, S. Laufer, E. Mutschler, J. Schweiger und H.G.Striegel : Regioisomeric 3-, 4- and 5-Aminomethyl- Isoxazoles : Synthesis and Muscarinic Activity, Eur. J. Med. Chem. 30, 839-850 (1995)

4) G. Dannhardt, W. Kiefer and U.Nowe : Non-steroidal Anti-inflammatory Agents, XIX : E-2- Pyrrolizin-5-yl Acrylic Acids as Potent Dual or Selective Inhibitors of Bovine Cyclooxygenase and 5- Lipoxygenase, Arch. Pharm. (Weinheim), 328, 681-686 (1995)

5) G. Dannhardt, W. Kiefer, G. Kreye, U. Nowe, H. Ulbrich : Pyrrolizinyl- and Indolizinyl-Acrylic and Acetic Acids and Pyrroles as Potent Dual or Selective Cyclooxygenase and 5- Lipoxy-genase Inhibitors, Prostaglandins Leukot. Essent. Fatty Acids (1996) 55, Suppl. 1, 99

6) G. Dannhardt, W. Kiefer, S. Laufer, H.-G. Striegel, K. Neher, P. Zechmeister, C. Donat, K. Stolingwa, S. Baur, S. Tries and T. Kammermeier : Synthesis and Evaluation of a Novel Series of Pyrrolizine Derivatives as Dual Cyclooxygenase-1 and 5-Lipoxygenase Inhibitors, Archiv der Pharmazie (Weinheim) 330, 307-312 (1997)

7) G. Dannhardt, W. Kiefer, U. Nowe, A.M. Sobottka, G.K.E. Scriba, W. Werner, G. Blaschke, E.E.S. Schapoval and E.P. Schenkel : Effect of Flavonol Derivates on the Carrageenin- Induced Paw Edema in the Rat and Inhibition of Cyclooxygenase and 5-Lipoxygenase in Vitro, Arch. Pharm. Pharm. Med. Chem. 333, 205-210 (2000)

8) G. Dannhardt, W. Kiefer, G. Krämer, S. Maehrlein, U. Nowe and B. Fiebich: The Pyrrole Moiety as Template for COX-1/COX-2- Inhibitors, Eur. J. Med. Chem. 35 (5), 499-510 (2000)

9) H. Weigmann, S. Härtter, S. Maehrlein, W. Kiefer, G. Krämer, G. Dannhardt and C. Hiemke: Simultaneous determination of olanzapine, clozapine and demethylated metabolites in serum by on-line column-switching high-performance liquid chromatography, J. of Chromatography B, Journal of Chromatography B 759, 63-71 (2001)

10) G. Dannhardt, W. Kiefer: Cyclooxygenase Inhibitors – Current Status and Future Prospects, Eur. J. Med. Chem. 36, 109-126 (2001)

11) G.Dannhardt, W. Kiefer, 1-Pyrrolines (3,4-Dihydro-2H-pyrroles) as a Template for New Drugs, Arch. Pharm. Pharm. Med. Chem. 334, 183-188 (2001)

12) W. Kiefer and G. Dannhardt: COX-2 inhibition and the control of pain, Curr. Opin. Invest. Drugs 3 (9), 1348-1358 (2002)

13) M.G. Banwell, A. Bezos, S. Chand, G.Dannhardt, W. Kiefer, U. Nowe, C. Parish, G.P. Savage, H. Ulbrich: Convergent synthesis and preliminary biological evaluations of the stilbenolignan (+/-)- aiphanol and various congeners, Org. Biomol. Chem. 1, 2427-2429 (2003)

14) W. Kiefer and G. Dannhardt: Novel Insights and Therapeutical Applications in the Field of Inhibitors of COX-2, Curr. Med. Chem. 11, 3147-3161 (2004)

15) W. Kiefer, G. Dannhardt: COX-2 inhibition and pain management: a review summary, Expert Rev. Clin. Immunol. 1 (3), 431-442 (2005)

16) G. Dannhardt, W. Kiefer: Antiepileptika - Wirkprinzipien und strukturelle Parameter, Pharm. Unserer Zeit 4, 270-281 (2007)

17) G.Dannhardt, W. Kiefer: Neue Antiepileptika in der Entwicklung, Pharm. Unserer Zeit 4, 306-310 (2007)

18) M. Scholz, H.K. Ulbrich, A. Mattern, J.-P. Kramb, W. Kiefer and G. Dannhardt: Investigations Concerning the Correlation of COX-1 Inhibitory and Hydroxyl Radical Scavenging Activity, Arch. Pharm. Chem. Life Sci., 341, 281-287 (2008)